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UID:0-333@aerospace.technion.ac.il

DTSTART;TZID=Asia/Jerusalem:20190318T163000

DTEND;TZID=Asia/Jerusalem:20190318T173000

DTSTAMP:20230527T132557Z

URL:https://aerospace.technion.ac.il/events/buckling-of-arteries-and-other
 -instabilities-in-soft-tissues/

SUMMARY:Buckling of Arteries and Other Instabilities in Soft Tissues
DESCRIPTION:Lecturer:Nir Emuna\n Faculty:Department of Aerospace Engineerin
 g\n Institute:Technion – Israel Institute of Technology\n Location:Class
 room 165\, ground floor\, Library\, Aerospace Eng.\n Zoom: \n Abstract: \n
  Details: \n In 1809\, almost a century before the first human flight\, th
 e polymath Thomas Young opened his lecture “On the functions of the hear
 t and arteries” with the following statement:\n“The mechanical motions
 \, which take place in an animal body\, are regulated by the same general 
 laws as the motions of inanimate bodies… As far\, therefore\, as the fun
 ctions of animal life depend on the locomotions of the solids or fluids\, 
 those functions must be capable of being illustrated by the consideration 
 of the mechanical laws of moving bodies: and it is obvious\, that the inqu
 iry\, in what manner\, and in what degree\, the circulation of the blood d
 epends on the muscular and elastic powers of the heart and of the arteries
 \, supposing the nature of those powers to be known\, must become simply a
  question belonging to the most refined departments of the theory of hydra
 ulics.”\nThis prophetic statement is materialized\, now\, more than ever
 . An increasing number of engineers\, mathematicians\, and physicists appl
 y analytical\, numerical\, and experimental methods that have matured in t
 hose disciplines\, to answer questions in biology. Mechanical stability an
 alysis\, a method well known to aeronautical\, mechanical\, and civic engi
 neers\, provides valuable insights into developmental processes (cortical 
 folding\, pattern formation in gastrointestinal tissues)\, neurological di
 sorders (schizophrenia\, polymicrogyria\, lissencephaly)\, arterial pathol
 ogies (atherosclerosis\, aneurysms\, thrombosis)\, to name a few. The intr
 insic complexity of these tissues poses quite a few modeling challenges. M
 any soft tissues have a layered structure\, each layer has different\, hig
 hly nonlinear and anisotropic mechanical behavior.  Due to differential g
 rowth taking place in the layers\, residual stresses are developed. Moreov
 er\, the boundary and interface conditions in soft biological tissues are 
 not known to the same level of certainty as in engineering structures.\nIn
  this talk\, I will be discussing the application of linear bifurcation an
 alysis to soft tissues within the framework of nonlinear elasticity. In pa
 rticular\, I will discuss twist buckling in arteries (as found in femoropo
 pliteal and testicular arteries)\, how sensitive are stability margins to 
 load configuration at the onset of instability (i.e. dead-load\, follower 
 force\, fluid-pressure)\, and how the joint effect of residual stresses an
 d interfacial conditions can induce spontaneous buckling (as found in esop
 hagus and airways). Given time\, I will also discuss the problem of sensit
 ivity of vascular constitutive models to uncertainties in residual stresse
 s data.
CATEGORIES:Seminars
LOCATION:Classroom 165\, ground floor\, Library\, Aerospace Eng.

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